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[2] Franois Couture, a reviewer for Allmusic, said that "Mystery Roach" contains multiple meanings, all of which have a connection to lyrical subject matter in Zappa's discography

You're more likely to get heartburn if you lie down on a full stomach

Such as tar, carbon monoxide, and hard particles contained in cigarette smoke

Nicotine and other chemicals in cigarettes can disrupt normal metabolic processes, leading to spikes in blood sugar levels

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