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Reduced activity or production of this anticoagulant factor would lead to an uncontrolled coagulation cascade that could extend beyond the damaged area, affecting other (undamaged) vascular districts and restricting local blood flow with consequent ischemic damages and more damage to the blood vessels

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Alcohol and benzodiazepines are often considered the hardest drugs to detox from because withdrawal from either one can be life-threatening

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Table 4 Demographic and behavioural factors associated with psychiatric diagnosis or help-seeking