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Long-Term Impact The most extreme complication is rheumatic heart disease, which may result in: Permanent heart valve damage Heart murmurs Heart failure later in life This condition remains a leading cause of preventable heart disease worldwide

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Other research suggests that smoking during pregnancy increases the risk of placental abruption (the separation of the placenta from the uterus), which can lead to hemorrhage and stillbirth, and placenta previa (the placenta implanting over the cervix), which can cause serious complications during childbirth and increase the likelihood of requiring a c-section, explains Aagaard

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