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PROPKA3: Consistent treatment of internal and surface residues in empirical p K a predictions

For example, proteins such as histone 1, H2A, H4, and leucine-rich repeat protein are overexpressed in antimony-resistant parasites, while proteins like the kinetoplastid membrane protein (KMP-11) are under-expressed (Kazemi-Rad et al., 2013)

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However, the EC50 of PV2-S71 + PV3-N77 was lower than PV2-S71pAcF and higher than PV2-N77pAcF, suggesting a compromise between two single variants (Fig

53 The detrimental effects are more pronounced with longer-chain SFAs, while monounsaturated fatty acids can mitigate these deficits by enhancing -oxidation and ATP production