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Raynaud phenomenon Antiphospholipid syndrome Cholesterol emboli Smoking and cutaneous lupus erythematosus There is more than ten-fold risk of chronic cutaneous lupus erythematosus (especially discoid lupus erythematosus) in smokers compared to non-smokers

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Also present in the fresh version are particles of reconstituted tobacco translucent particles devoid of texture

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The teenage brain is particularly vulnerable