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In addition, activation of the NADPH oxidase is linked to changes in the structure and function of cerebral arterioles that are associated with small vessel disease [49], and to angiotensin II-dependent activation of the enzymatic complex that increased oxidative stress and hypertension in both rats and endothelial cells [43]

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Patients were grouped as smokers and non-smokers

and Slotkin, T.A., "Cocaine exacerbates hypoxia-induced cell damage in developing brain: effects on ornithine decarboxylase activity and protein synthesis," Biol

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