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The lung damage often gets worse over time, and is usually permanent

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Even when you smoke a little bit

Human studies report varied outcomes, revealing modest changes in immune cell composition, increases in certain cytokines and enzymes, and decreased protective proteins, with acute injury boosting proinflammatory signals

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Tob Control 27:1017 Flanders WD, Lally CA, Zhu BP, Henley SJ, Thun MJ (2003) Lung cancer mortality in relation to age, duration of smoking, and daily cigarette consumption: results from Cancer Prevention Study II