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Among studies analyzing risk and protective factors, as well as motives for EC use, arranged from lower to higher quality in study design, there is one case-control study 60 , one discrete choice experiment 63 , 18 cross-sectional studies 47,50-53,55-58,64,66,67,70,71,75,78,79,96 , 8 longitudinal studies 54,61,62,68,74,76,77,80 , and 2 randomized controlled trials 49,59

While flexible cartons are designed for easy packing, rigid boxes are made to be strong and secure, making them great for use in stores and when being shipped

Elsewhere, the change has been much more dramatic

FIGURE 6

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