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NRT comes in a number of forms, including: patch gum lozenge inhaler nasal spray Signs of a severe nicotine allergy Call your doctor immediately or get to a hospital emergency room if you experience signs of a severe allergic reaction, including: difficulty breathing swelling of your face, lips, tongue, or throat hives Other serious side effects of nicotine may include: irregular heartbeat chest pain seizure Many allergists when testing for tobacco smoke allergies will test for allergies to the chemicals in tobacco products like cigarettes