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The developing brain is more sensitive to nicotines effects, and young people produce stronger dopamine responses, so the brain learns faster that nicotine equals reward

These measures, often termed cognitive elaboration, are well-validated and often used in studies of cigarette health warnings (See, e.g., Refs

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In particular, he points out that the mechanistic studies highlighted - i.e

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This is because when you inhale, the oxygen travels through your lungs and into your heart, where it is pumped throughout the rest of your body through your blood vessels