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Mechanistically, IF reduces systemic inflammation, alters the distribution of adipose tissue, and increases thermogenesis, which in turn supports insulin signaling pathways and enhances metabolic flexibility [49]

International Agency for Research on Cancer, 170, 2015

FXR, Farnesoid X Receptor

Consequently, the direct regulation of transporters and enzymes within metabolic pathways, as well as the indirect regulation of Gln metabolism through the modulation of associated oncogenes and ncRNAs, may represent promising avenues for future cancer therapies

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