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Commonly-used definitions of youth e-cigarette use have been adapted from measures validated for tobacco cigarette smoking among adults, but may not carry the same meaning for a different product (with a much lower risk profile and very different patterns of use) and a different population (whose use is more often transient and experimental, rather than frequent and persistent)

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23 A review of four studies spanning over 500,000 individuals found that those who vape have a significantly higher risk of a heart attack than people who do not use vapes