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It seems that the high smoking prevalence among Asian men adds to the smoking-attributable cases, while RRs have been observed to be lower in Asia than in Western countries

"The real heart of the problem is that most people who buy these cigarettes down the pub or on holiday don't really think it is anything illegal." "They see that on the continent they can buy cigarettes at half the price than in the UK and think thanks very much we'll have some of that." A delegation of Tobacco industry executives are calling for a reduction or freeze on duty arguing against the governments line that high taxes discourage smoking but instead just provides the perfect condition for a thriving black market to continue.

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Specific protein 1 (Sp1) is a ubiquitous, stress-activated transcription factor in the nucleus that regulates genes involved in apoptosis and senescence [21]