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The ER has a significantly more oxidized environment compared with the cytosol to allow oxidation of cysteine residues in nascent polypeptide chains to form intramolecular disulfide bonds

150 Moreover, CCL5, expressed by hepatocytes, can activate M1 macrophage polarization and impede liver repair following AILI

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doi: 10.1515/znc-1995-5-619 24 GullnerG.TobiasI.FodorJ.KmivesT

Indeed, various endogenous of dietary antioxidants are capable of ameliorating steatohepatitis and OXA-induced neurotoxicity via reducing oxidative stress