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While the general consensus has been that vaping or use of e-cigarettes in place of lighting up tobacco is exponentially healthier than inhaling the 7,000+ chemicals (including 69 known carcinogens) of a cigarette, there has remained some question as to whether vapingespecially for young people whove never smoked cigarettes beforecould be a gateway to smoking tobacco

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49-53 Nicotine also dysregulates ions and glucose transporters (GLUT1 and GLUT3) in cerebral microvessels and increases BBB permeability, in part by reducing the expression ofand adversely alteringthe cellular distribution of several tight junction proteins

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