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Moreover, arginase 2 (Arg2) , another direct target for miR-155, when repressed prevents the depletion of L-arginine, the obligate substrate of eNOS, leading to improved substrate availability and additional increases in NO production and NO bioavailability, further aiding the above-mentioned NO antiviral actions [74]

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Sample size determination The sample size for the study has been calculated based on the volume of smoke inhaled by participants, which is one of the primary outcome measures

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