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We weighted estimates to represent the US adult population and estimated standard errors and 95% confidence intervals (CIs) using the balanced repeated replication method [28] with Fays adjustment set to 0.3 to increase estimate stability [29]

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Methods: We commissioned systematic reviews on evidence of benefits and harms of smoking cessation interventions in adults, comprising an overview of Cochrane reviews on behavioural interventions, pharmacotherapy, and other interventions, and a systematic review on electronic cigarettes (e-cigarettes)