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Nicotine Delivery and Vaping Behavior During ad Libitum E-cigarette Access

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For this type we recommend the following vape juice: 50PG / 50VG e-liquid 40PG / 60VG e-liquid Nicotine salt e-liquid Sub Ohm/Direct to Lung (DTL) The second are sub ohm vape pens that has coils with a resistance below 1.0 Ohm

Nicotine C-oxidation to nicotine 5(1)iminium ion is followed by a second oxidation that generates cotinine, which is further metabolized to trans 3-hydroxycotinine (3-HCOT), a reaction that is catalyzed almost exclusively by CYP2A6 (see Fig