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[93] Continuous exposure to nicotine can cause an increase in the number of nicotinic receptors, which is believed to be a result of receptor desensitization and subsequent receptor upregulation

But here's the thing you should keep in mindyour body is already working hard to adjust to life without tobacco

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The majority of EVALI cases occurred in the United States, and was strongly linked to e-cigarettes containing 9 -THC where vitamin E acetate (VEA) was used as a diluent in black-market products [194]