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North Carolina has a rich history of agricultural and economic prosperity, much of which can be attributed to the ecological and biological exchange that occurred during the Columbian Exchange

Nicotine Burden 1.1 Billion smokers globally 1 1 Billion lives could be lost this century 2 6 Million pre-mature deaths annually 2 $2 Trillion annual costs of smoking related illness worldwide 3 150 Million individuals globally live with a serious illness due to nicotine addiction caused by smoking, and more than 40%, continue to smoke

Mortaheb S, et al

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Repeat twice a day until healed

One half or more of the cases of severe gum disease in American adults may be due to cigarette smoking