"Most people know that using tobacco causes cancer and lung disease, but many people arent aware that tobacco also causes heart disease and stroke the worlds leading killers," said Dr Tedros Adhanom Ghebreyesus, WHO Director-General
Abbreviations ACPA: anti-citrullinated protein antibody AM: alveolar macrophage CCP: cyclic citrullinated peptide EBV: EpsteinBarr virus HLA: human leukocyte antigen IFN: interferon IL: interleukin LPS: lipopolysaccharide NARAC: North American Rheumatoid Arthritis Consortium NF: nuclear factor PAD: peptidyl arginine deiminase PTPN22: protein tyrosine phosphatase nonreceptor 22 RA: rheumatoid arthritis RF: rheumatoid factor SE: shared epitope siRNA: small interfering RNA SONORA: Study of New Onset Rheumatoid Arthritis TNF: tumor necrosis factor
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