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We consider, however, that the study is worth doing even if the results are only weakly informative, as we are exploring several other forms of tobacco and nicotine use and our estimates can be meta-analysed with future studies to obtain more precise estimates 49

doi: 10.1136/bmjresp-2021-001105 22

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For cocaine intake above 3 grams, there is a high risk of life-threatening cardiac arrhythmias, and the patient must be monitored in a unit equipped with cardiac monitoring and emergency interventions for ventricular fibrillation