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Other pathophysiological mechanisms by which cigarette smoke can alter cytokine gene transcription rely on smoke-induced changes to the epigenome, such as DNA methylation, expression of microRNA and histone modification [96,97]

Prosecutors said Border Patrol agent Charles Exum shot Martinez in self-defense after she and another person allegedly rammed their cars into a federal vehicle on Oct

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The rest of the story is about how theyre made, how theyre used, what they mean in the culture, and why so many people sense such a gulf between them even as public-health agencies warn that neither is harmless

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