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2010, Neurobiological mechanisms involved in nicotine dependence and reward: participation of the endogenous opioid system. This neurotransmitter release results in feelings of pleasure and reward, reinforcing the addictive nature of tobacco use

This mostly keeps you from breathing in large particles, but tar, nicotine and other chemicals still get through

(2023, November 2)

Because tobacco contains addictive ingredients, prolonged and even one-time usage of tobacco products can lead to life-lasting health issues such as smokers lungs

doi:10.1093/toxsci/64.1.4

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