On the AX12, AX iAECs were maintained in AX Alveolar Epithelial Barrier Medium (AlveoliX, Switzerland) supplemented with 1% penicillinstreptomycin (Thermo Fisher Scientific, Switzerland) for mono-culture studies and AX iAECs/hLMVECs were maintained in AX E2 Alveolar Barrier Medium (provided by AlveoliX) for all dual-culture studies
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We are grateful for the support the European Commission has provided to obtain these data. Tobacco is well known as a modifiable contributor to adverse health outcomes, and it has been estimated to have caused 7.69 million deaths globally in 2019, with numbers expected to increase in the future
These misperceptions may therefore impede efforts to encourage smokers ready to quit to use evidence-based cessation support such as nicotine replacement during quit attempts and limit the success of policies designed to shift smokers to less harmful sources of nicotine