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We also found that p-STAT3 expression was significantly increased in mice premetastatic lungs/neutrophils, which was reversed by STATIC treatment, as well as in smokers lung metastasis lesion (Supplementary Fig

This means that the system is particularly designed to be activated by aversive stimuli. To demonstrate this for nicotine, Liu and her colleagues infused the drug into mice and measured the second-by-second release of dopamine in the brain using a recently developed technique called dLight-based fiber photometry

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