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The cultural impact was immediate and profound, though it would take decades for that impact to fully manifest in behavioral changes

The first to suffer are the teeth, gums, tongue and lips

Retrieved September 19, 2025

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[85] The WHO in 2004 projected 59 million deaths to occur globally, [86] : 8 from which 5.4 million are smoking-attributed, [86] : 23 and 4.9 million as of 2007

The target sample size was 636, based on power analysis for the primary research question using G*Power, with 90% power to determine an effect size (f2) of 0.02 on our primary outcome at an alpha level of 0.05