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The more chemicals contained in an e-liquid, the more toxic it was likely to be, the authors wrote

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And a particular rise in all kinds of smoking has been seen in those aged 18 to 24

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PMID: 842646 Kawashima K et al (1988): Direct determination of acetylcholine release by radioimmunoassay and presence of presynaptic M1 muscarinic receptors in guinea pig ileum

42 For many decades, our government enabled nicotine addicts to smoke wherever they liked, while non-smokers were not adequately informed of the dangers of second-hand smoke inhalation