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However, in the US, each pack of cigarettes contains 20

However, recent ultra-performance liquid chromatography-tandem mass spectrometry in female wildtype mice exposed to ENDS for 4 weeks, 1 hour per day with a 25 mg/mL nicotine concentration, determined cotinine levels of 362.3\(\pm\)16.27 ng/mL 30

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More research is needed, but we know that the acute effects on heart rate and blood pressure are significant, especially in people with pre-existing hypertension (high blood pressure)

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