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Jackson et al., Changing Patterns of Nicotine Product Use and Nicotine Dependence Among United States High-School Students: The National Youth Tobacco Survey, 20142023, Addiction , June 25, 2025, Data extracted from Centers for Disease Control and Prevention, National Survey on Drug Use and Health. Assessing the size of the illicit and untracked market is inherently difficult

These microbiome alterations correlated with lung function decline, including reduced forced vital capacity (FVC) and increased inflammation markers