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The toxic substances in cigarette smoke cause significant inflammation and excessive mucus production in the lungs, which, combined with the destruction of cilia, severely impair respiratory function

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Halpern reported the number of deaths per years of life in 196,529 current smokers, 212,050 former smokers and 444,210 never smokers and also stated the relative risk of lung cancer death in former smokers who quit at different ages, compared to (i.e