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Patients affected by the disease have symptoms ranging from cough, chest pain, and shortness of breath to fatigue, vomiting, and fever

This causes circulation issues because your tissues are unable to get the appropriate amount of oxygen

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Picchio V, Ferrero G, Cozzolino C, Pardini B, Floris E, Tarallo S, Dhori X, Nocella C, Loffredo L, Biondi-Zoccai G, Carnevale R, Frati G, Chimenti I, Pagano F (2024) Effect of conventional or heat-not-burn cigarette smoking on circulating miRNAs in healthy subjects