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We observe that self-replicators arise mostly due to self-modification and this can happen both with and without background random mutation

Affordability : A cost-effective option without compromising quality

I want a smoke.' And you'll say, kind of careless like, as if it warn't anything, you'll say, 'Yes, I got my old pipe, and another one, but my tobacker ain't very good.' And I'll say, 'Oh, that's all right, if it's strong enough.' And then you'll out with the pipes, and we'll light up just as ca'm, and then just see 'em look!" - Mark Twain, The Adventures of Tom Sawyer (1876) Tagged in: Famous Pipe Smokers Pipe Culture Quotes Tobacco

Furthermore, smoking inside a home may signal a broader pattern of indoor environmental neglect

VINCENT Well what then

The old regime was clearly unsustainable