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The collagenase model replicates the matrix disorganization and degenerative pathology of clinical tendinopathy more closely than transection models, strengthening the relevance of the findings to the human chronic tendinopathy condition

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New inhibitors for the neutral amino acid transporter ASCT2 reveal its Na+-dependent anion leak

: (Tyrosinase):

doi: 10.1371/journal.pone.0183509

Starting with lower doses and increasing gradually allows assessment of personal tolerance before committing to full therapeutic doses