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Patients with extra risk factors may be more susceptible to cardiovascular events due to platelet activation and changes in the ratio of tissue plasminogen activator to plasminogen activator inhibitor (179, 197)

The OuLiPo has had as its purpose the invention and rediscovery of what the French call contraintes ;and we call, for want of a better word, constrictive forms

Thus, by mixing them, their effects can combine or add up

It increases the risk of lung cancer, heart attack and chronic obstructive pulmonary disease (COPD)

Cigarette cards found a cosy home in tin boxes or albums, cherished for their nostalgic value and collectability

Sounds entertaining, and fun, to me