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Despite these regulations, the use of vaping devices is increasing among youth

Even though smoking rates have hit record lows in the U.S., 34.3 million adults or 14% of adults still smoke, according to the Centers for Disease Control and Prevention

Pharmacological withdrawal itself may have substantial effects on brain activation to cues, either by obscuring or enhancing it, and as CIC is not reduced by nicotine replacement strategies, its neuro-anatomical substrates may differ

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