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A second reason is that one does not know whether these mixtures behave according to a linear combination of the effects of their individual constituents or whether synergistic effects occur

They include nicotine vapes (e-cigarettes), tobacco-free nicotine pouches , Swedish-style snus (an oral tobacco), many US smokeless (chewing) tobaccos and heated tobacco products

The surgeon general says that a simple drag on a cigarette can be deadly

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doi:10.5888/pcd17.200161 [20] Emerson E