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SHS-exposed chronic bronchitis dogs had statistically significantly higher median values of inflammatory cells (total nucleated cells and macrophages) in comparison to non-SHS exposed dogs, but methylations rates and concentrations of DNA were not statistically significantly associated with SHS exposure 38

This usually requires open flame or thick, heavy smoke, which won't usually be a problem for vapor

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smoking rate, which has leveled off at around 18% of the adult population for a decade, moving lower again

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