This analysis revealed that successful quitters randomized to placebo reported a large decrease from pre-quit to 1 year post-quit in the percentage of prompts at which smoking was permitted at their location (from 84 to 52% of the time), while quitters randomized to at least some bupropion reported a small decrease (from 83 to 76%), and quitters randomized to receive only nicotine replacement therapy reported an intermediate decrease (from 85 to 71%)
This study shows that when smokers interested in reduction are provided with an e-cigarette that has cigarette-like nicotine delivery, they are more likely to achieve significant decreases in tobacco-related toxicants, such as lower exhaled carbon monoxide levels. The researchers conducted a randomized controlled trial of 520 participants who smoked more than nine cigarettes a day, were not currently using an e-cigarette device, and were interested in reducing smoking but not quitting
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In utero exposure to nicotine, which is found in many vaping products, is known to directly harm fetuses by causing abnormal lung, heart, brain, and immune system development, which carries lifelong consequences." Robyn Horsager-Boehrer, M.D