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NAD+ is the exception its sting is acidity-driven, so NaCl helps only the osmotic part and buffering the pH helps more. How does injection site affect repair-peptide distribution, and does proximity to an injury matter

doi: 10.3389/fcell.2025.1737456 Received 01 November 2025 Revised 14 December 2025 Accepted 22 December 2025 Published 12 January 2026 Volume 13 - 2025 Edited by Silvia Masciarelli, Sapienza University of Rome, Italy Reviewed by Xuchang Zhou, The First Affiliated Hospital of Xiamen University, China Weibei Sheng, Peking University, China Updates Copyright 2026 Zhang, Li, Yang and Yang

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