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In Canada, similar trends are emerging, with around 6% of Canadiansapproximately 1.8 million peoplehaving used e-cigarettes in 2022

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They appear in white wrinkly patches, and although they are not cancerous to begin with, with long term use, the cells begin to change and spread and can eventually turn into cancer. According to Lanphier, after long term use, the leukoplakia can spread too deep in the gums to the point where it becomes irreversible, but can be healed if the user quits in the early stages

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