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Tobacco, whether smoked or chewed, contains nicotine - a potent stimulant that causes your blood vessels to constrict and your heart to beat faster

However, this much is clear that the long-term use of tobacco has been linked to it

2 with age on the horizontal axis and each birth cohort represented by a line (Additional file 1: Figure S3), providing a complementary perspective of the smoking epidemic in the high-income regions

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If you were to point out to him the Dowager Lady Grimgriffin acting as chaperon to Lady Amanda Creamville, he would imagine you were referring to the petit Chaperon rouge to little Red-Riding Hood