Project 1 is now co-led by Zachary Bitzer, assistant professor of public health sciences, and Thomas Spratt, professor of biochemistry and molecular biology
Then, due to the proximity that macrophages and tumor cells reside in, interactions between VCAM-1 and the 4 integrins are promoted, which recruit Ezrin, a cytoplasmic adaptor protein that links the actin cytoskeleton to the cytoplasmic tail of VCAM-1, and ultimately results in tyrosine phosphorylation of Ezrin
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