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These effects did not reduce with the inclusion of household structure variables alone (Supplementary Table 2)

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Bibcode:2005Pedia.116.e113K

The authors did not identify any widespread differential effects of smoking cessation pharmacotherapies based on genotype

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Compared with people who don't use, long-term, heavy marijuana smokers tend to have a smaller orbitofrontal cortex (OFC), a brain region critical for processing emotions and making decisions