[36] Some of the health risks of tobacco smoking in general, that have been identified, are: Chronic chest infections [37] [38] [39] Obstructive pulmonary disease [40] [11] Increased risk of larynx, [41] respiratory [42] or other organ cancers [43] [44] Nicotine dependence and tolerance, increased risks of nicotine poisoning Chemical composition [edit] A February 2018 study called for further research into the harmful effects of dokha smoke after it found that three different types of dokha tested from the Middle East and North Africa region contained toxic metals comprising "22 irritants, 3 known carcinogens, 5 central nervous system depressants, in addition to several other compounds with miscellaneous effects"
That 1964 surgeon generals report on smoking and health spurred profound and lasting changes in tobacco use and policies in the United States, but its call to action has gone unfulfilled internationally
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They are suitable for using with regular size 70mm cigarette rolling papers, and can be used with or without a filter tips
P -values less than 0.05 were considered to indicate statistical significance
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