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5-fluoro MDMB-PINACA (5F-ADB) is a synthetic cannabinoid that has been linked to a series of five non-fatal clinical intoxications after smoking Spice or herbal preparation to cause anxiety, confusion, psychomotor agitation, psychosis and tachycardia

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The irritation is caused by the hot, dry air that removes any moisture from the throat that helps to keep it lubricated