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So we know that smoking damages the skin, but unlike sun damage that only affects areas of the skin that have been exposed to UV light, smoking affects skin all over the body, from your head down to your toes

Southwest China Sci Rep 12(1):2815

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Preventive Medicine , 47 (4), 447451

Further to the above, the Directive also provides specific product requirements for electronic cigarettes, such as maximum nicotine levels (20 mg/mL), volume requirements for refill containers and cartridges, and mechanical requirements for electronic cigarettes and refill containers