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It causes a degree of inflammation similar to bronchitis or cigarette smoking

Specifically, the pooled ORs for current, former, and ever e-cigarette users were 1.473 (95% CI: 1.2601.723), 1.766 (95% CI: 1.4182.200), and 1.388 (95% CI: 1.0702.458), respectively, indicating that individuals who use or have used e-cigarettes face significantly greater odds of having COPD

Clearly this could not be done, so, in this example, one has to rely on other types of evidence. Hill and Doll tried to find that evidence in the hospitals of London

We also spoke with Amy Barkley, a regional advocate for the Campaign for Tobacco-Free Kids.