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21 Furthermore, in individuals with multiple sclerosis who smoke, there is an increased frequency of GPR15 + CD4 + T cells exhibiting Th17-like characteristics, implicating GPR15 as a potential link between environmental exposure and autoimmune pathogenesis

We also mentioned carbon monoxide as one of the components of smoke

Peter Selby and Laurie Zawertailo (both of the University of Toronto) that summarizes the latest in the literature

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