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last year lost a case at the WTO when appellate judges at the Geneva-based organization upheld a ruling that a law banning clove cigarettes is discriminatory because it accords clove cigarettes less favorable treatment than that accorded to domestic menthol-flavored cigarettes. Indonesia, the largest maker of clove brands, brought that case
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However, ex vivo exposure of neutrophils to e-cigarette aerosols found significant reduction in chemotaxis, dysfunctional F-actin polarization and membrane fluidity, reduced ROS production, reduced PMA-induced NETosis, and diminished phagocytosis, although this reduced activity seems to be independent of nicotine(50-52)
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